Journal article
Analyses of thrombi in acute ischemic stroke: A consensus statement on current knowledge and future directions
SF De Meyer, T Andersson, B Baxter, M Bendszus, P Brouwer, W Brinjikji, BCV Campbell, V Costalat, A Dávalos, A Demchuk, D Dippel, J Fiehler, U Fischer, M Gilvarry, MJ Gounis, J Gralla, O Jansen, T Jovin, D Kallmes, P Khatri Show all
International Journal of Stroke | Published : 2017
Abstract
Limited data exist on clot composition and detailed characteristics of arterial thrombi associated with large vessel occlusion in acute ischemic stroke. Advances in endovascular thrombectomy and related imaging modalities have created a unique opportunity to analyze thrombi removed from cerebral arteries. Insights into thrombus composition, etiology, physical properties and neurovascular interactions may lead to future advancements in acute ischemic stroke treatment and improved clinical outcomes. Advances in imaging techniques may enhance clot characterization and inform therapeutic decision-making prior to treatment and reveal stroke etiology to guide secondary prevention. Current imaging ..
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Awarded by National Institute of Neurological Disorders and Stroke
Funding Acknowledgements
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Travel support for the Clot Summit was provided by Neuravi. This work was supported by the Fonds voor Wetenschappelijk Onderzoek Vlaanderen, G.0A86.13, G078517N and 1509216N (to S.F.D.M), an 'Onderzoekstoelage' grant from KU Leuven (OT/14/099 to S.F.D.M) and an NINDS-NIH grant K24NS072272 (DSL). B.C.V. Campbell: reports research support from the National Health and Medical Research Council of Australia (GNT1043242, GNT1111972, GNT1113352), National Heart Foundation (Future Leaders Fellowship 100782), unrestricted grant funding for the EXTEND-IA trial to the Florey Institute of Neuroscience and Mental Health from Covidien (Medtronic). PK has received funds from Novartis/Medpace (coinvestigator), Biogen (DSMB member), St Jude (consultant); Grand Rounds (online clinical consultant), and UpToDate (royalties). Her Department of Neurology also received funds from Genentech (PRISMS Lead PI) and Penumbra (THERAPY Neurology PI). A.J. Yoo receives research support for core imaging lab activities from Penumbra Inc. and Neuravi Inc. C.B. Majoie reports research support from the Dutch Heart Foundation; AMC (Dr. Majoie's institution) received funds from Stryker for consultations by CBM. DWJ Dippel reports research support from the Dutch Heart Foundation; Erasmus MC (Dr Dippel's institution) received funds from Bracco Imaging and Stryker for consultations by DWJ Dippel.